foods that may protect DNA include kiwifruit (Kiwifruit and DNA Repair), cruciferous vegetables (DNA Protection from Broccoli), leafy vegetables (Eating Green to Prevent Cancer), garlic (Cancer, Interrupted: Garlic & Flavonoids), green tea (Cancer, Interrupted: Green Tea (but which is better? Antimutagenic Activity of Green Versus White Tea), and plants in general (Repairing DNA Damage).
Curcumin comes no.1
I also researched and read that black raspberry from Oregon has cancer protection potential.
I researched and found from pub med some good information.
Cancer Lett. 2008 Oct 8;269(2):281-90. doi: 10.1016/j.canlet.2008.05.020. Epub 2008 Jun 20.
Anthocyanins and their role in cancer prevention.
Wang LS1, Stoner GD.
Author information
Abstract
Anthocyanins are the most abundant flavonoid constituents of fruits and vegetables. The conjugated bonds in their structures, which absorb light at about 500 nm, are the basis for the bright red, blue and purple colors of fruits and vegetables, as well as the autumn foliage of deciduous trees. The daily intake of anthocyanins in residents of the United States is estimated to be about 200 mg or about 9-fold higher than that of other dietary flavonoids. In this review, we summarize the latest developments on the anti-carcinogenic activities of anthocyanins and anthocyanin-rich extracts in cell culture models and in animal model tumor systems, and discuss their molecular mechanisms of action. We also suggest reasons for the apparent lack of correlation between the effectiveness of anthocyanins in laboratory model systems and in humans as evidenced by epidemiological studies. Future studies aimed at enhancing the absorption of anthocyanins and/or their metabolites are likely to be necessary for their ultimate use for chemoprevention of human cancer.
PMID: 18571839 [PubMed - indexed for MEDLINE] PMCID: PMC2582525 Free PMC Article
Images from this publication.See all images (2)Free text
The anthocyanins come from purple and blue fruits and vegetables like black raspberries,
Blackberries,blueberries,purple cabbage,purple potatoes
Cancer Prev Res (Phila). 2009 Mar;2(3):187-94. doi: 10.1158/1940-6207.CAPR-08-0226. Epub 2009 Mar 3.
Foodstuffs for preventing cancer: the preclinical and clinical development of berries.
Stoner GD.
Author information
Department of Internal Medicine, The Ohio State University, Innovation Centre, 2001 Polaris Parkway, Columbus, Ohio 43240, USA. gary.stoner@osumc.edu
Abstract
Laboratory research involving berries is a promising example of food-based cancer prevention. Berries contain many known chemopreventive agents such as anthocyanins and ellagitannins that can be greatly concentrated in freeze-dried berry powders. Based on our program of berry research, this commentary presents the first reported stepwise scheme for the preclinical and clinical development of foodstuffs for cancer prevention. Our preclinical work within this scheme includes promising approaches for assessing the chemopreventive potential of berry powder and berry extracts in preclinical model systems, for determining the mechanisms of action of these agents, and for identifying the active constituents in berries. The commentary also presents preliminary results of clinical trials in the oral cavity, esophagus, and colon using various formulations of freeze-dried berries. The relative merits of berry powders, extracts, or individual constituents (anthocyanins) for cancer prevention are also discussed.
PMID: 19258544 [PubMed - indexed for MEDLINE] PMCID: PMC2769015 Free PMC Article
Images from this publication.See all images (2)Free text
Display Settings:AbstractSend to:
J Agric Food Chem. 2005 May 18;53(10):3909-15.
Black raspberry extract and fractions contain angiogenesis inhibitors.
Liu Z1, Schwimer J, Liu D, Greenway FL, Anthony CT, Woltering EA.
Author information
Abstract
Targeted therapies, such as agents that inhibit angiogenesis, offer hope as complementary agents in cancer therapy. Angiogenesis-inhibiting agents have the potential for inhibiting tumor growth and limiting the dissemination of metastasis, thus keeping cancers in a static growth state for prolonged periods. Black raspberry (Rubus occidentalis) extract was discovered to be antiangiogenic (0.1% w/v) in a novel human tissue-based in vitro fibrin clot angiogenesis assay. Assay-guided fractionation of a crude black raspberry extract resulted in a highly potent antiangiogenic fraction that accounted for only 1% of the fresh weight of whole black raspberries. At 0.075% (w/v), the active fraction completely inhibited angiogenic initiation and angiogenic vessel growth. Further subfractionation of this active fraction revealed the coexistence of multiple antiangiogenic compounds, one of which has been identified as gallic acid. However, the individual subfractions did not outperform the active whole fraction. These findings suggest that an active black raspberry fraction may be a promising complementary cancer therapy. It is natural and potent enough for manageable dosing regimens. These extracts contain multiple active ingredients that may be additive or synergistic in their antiangiogenic effects. These observations warrant further investigations in animals and human trials.
PMID: 15884816 [PubMed - indexed for MEDLINE]
I experimented today in my blog some authentic info and scientific information,research based.
No comments:
Post a Comment