Please Read This First

In case of an emergency, please call 911 or ambulance or go to the nearest emergency room.

This blog is for information only. Dr. Dave will not respond to comments.

The information you obtain at Brazosdoctors.com or this blog is not and not intended to be a medical advice. You should consult a medical doctor for individual advice regarding your health. The use of the Internet for communications with the doctors will not establish any MD-patient relationship and messages containing confidential information, personal health or emergency should not be sent to the website or the blog.

Wednesday, February 10, 2016

PPI

Do you know what are PPI's?
I weaknessemusclse n cau have cahProton pump inhibitors! The most common prescription pill us d for heart burn or reflux symptoms.
Yes!it helps heartburn but do you know th side effects?
The most recent published data in Jan 2016 JAMA,prestigious medicine journal reveals they have been linked to acute interstitial nephritis,and CKD ( chronic kidney disease).
It is felt that these medicines are over prescribed and everyone who ncluding patients are not familiar with the bad side effects.
It can cause low magnesium ,muscle twitching,cardiac arrhythmia so.
Just supplementing magnesium may not be enough to correct the d fiche chinless PPIs are discontinued.
It can make you prone to Clostridium difficille infection.PPI reduce gastric acidity which promote colonization of these bad bacteria.
There is increased incidence of pneumonia.
Patients with Coronary artery disease and bypasses are generally prescribed anti platelet therapy
To reduce risk of coronary eventsPPi's are concurrently prescribed to prevent Gastrointestinal bleeding.
Plavix( generic clopidogrel)is metabolized to active forms by liver enzymes that also metabolize PPI's.
The competitive metabolism may lead to reduced activation of placid,reduced anti platelet effect and increased cardiac events.
Use of PPI's May decrease bone density and increase fracture risk.
One must check magnesium levels,serum creatinine for kidney function

No comments:

Post a Comment